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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1768144Generated: October 26, 2026

Methylamine → (RS)-2-Oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic Acid Methylamide

https://huagongshe.com/reaction/1768144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant(RS)-2-oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acidHCID 23614753—
Product(RS)-2-Oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic Acid MethylamideHCID 10249925—

Reaction Steps

The title compound is prepared in analogy to Example 6d) from (RS)-2-oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acid and methylamine. Yield: 6% of a colorless solid. MS: m/e=393.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07235581B2
Source datasetuspto-grants-2007_06
ORD IDord-92b3761a1c70436490085d34bdb5b909
Source noteuspto-grants-2007_06