Iodoethane → HCID 86748352, compound

Participants

Reaction Steps

A solution of 2.8 g of 5-[1-N-ethyl-3,4-dimethoxybenzimidoyl)-1,2,3,4-tetrahydroquinolin-6-yl]-6,6-dimethyl-3,6-dihydro-2H-1,3,4-thiadiazin-2-one (m.p. 188°) in 40 ml of dimethylformamide is treated with ice-cooling with 0.3 g of NaH and the mixture is stirred for 1 hour. 1.5 ml of ethyl iodide are then added, the mixture is stirred fur a further 2 hours and, after customary working up, 5-[1-N-ethyl-3,4-dimethoxybenzimidoyl)-1,2,3,4-tetrahydroquinolin-6-yl]-3-ethyl-6,6-dimethyl-3,6-dihydro-2H-1,3,4-thiadiazin-2-one is obtained.

Provenance & Evidence