Ammonium Hydroxide → 1-Amino-3-(morpholin-4-yl)propan-2-ol

Participants

Reaction Steps

500 mg of the 1-morpholino-2,3-epoxypropane prepared as described above were dissolved in 20 ml of a saturated methanolic solution of ammonium hydroxide, and the mixture was allowed to stand at room temperature for 3 days. At the end of this time, the reaction mixture was concentrated by evaporation under reduced pressure, to give 530 mg of 1-amino-3-morpholino-2-propanol.

Provenance & Evidence