Dicyclohexylamine → HCID 18948407, compound

HRID 1768603Notes

Reaction equation

HRID 1768603 reaction equation
Br[CH2:2][C:3]([O:5][CH3:6])=[O:4].[CH:7]1([NH:13][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1>C1C=CC=CC=1>[CH:14]1([N:13]([CH:7]2[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]2)[CH2:2][C:3]([O:5][CH3:6])=[O:4])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

4

Reactant 2

HCID 7582DicyclohexylamineHCID 60984Methyl bromoacetate

Product 1

HCID 18948407HCID 18948407, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

3.06 g (20 mmole) of methyl bromoacetate were added, whilst ice-cooling, to a solution of 7.25 g (40 mmole) of N,N-dicyclohexylamine in 50 ml of dry benzene, and the mixture was heated under reflux for 9 hours. At the end of this time, the reaction mixture was cooled, the precipitated materials were removed by filtration, and the filtrate was concentrated by evaporation under reduced pressure, to afford 5.07 g of the title compound as an oily substance.

Workup

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 9 hours
  3. temperatureAt the end of this time, the reaction mixture was cooled
  4. customthe precipitated materials were removed by filtration
  5. concentrationthe filtrate was concentrated by evaporation under reduced pressure

Sources & evidence

ORD record
ord-35ae088f279b48e18729977f18dd0126
Source dataset
uspto-grants-1995_01
Patent number
US05378690

Reaction notes

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