Hydrogen Bromide → 1-Decanol, 10-bromo-
Reaction equation
[CH2:1](O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11].[BrH:13]>>[Br:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11]Participants
3
Procedure
A solution of 50 g of decane-1,10-diol in 300 ml of 48% aqueous hydrobromic acid was heated at 90° C. for 24 hours while the solution was extracted continuously with petroleum ether 100-140. After cooling to room temperature, the petroleum ether solution was evaporated and the residue was purified by distillation. Boiling point 121°-124° C. (0.1 mm Hg).
Workup
- extractionwas extracted continuously with petroleum ether 100-140
- customthe petroleum ether solution was evaporated
- distillationthe residue was purified by distillation
Sources & evidence
- ORD record
- ord-6439186eebd647a88689e9a1961da681
- Source dataset
- uspto-grants-1995_01
- Patent number
- US05378718
Reaction notes
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