Ammonium Hydroxide → 4-(2,2-Dimethyl-1-oxopropyl)-benzamide

Participants

Reaction Steps

3.1 grams (14 mmoles) of 4-(2,2-dimethyl-1-oxopropyl) benzoyl chloride is dissolved in 15 milliliters of diethylether, and the resulting solution is added dropwise to concentrated ammonium hydroxide with vigorous stirring at 0°-10° C. The white crystalline precipitate which forms is filtered off and washed with water and with ether. The product is dried in vacuo to yield 4-(2,2-dimethyl-1-oxopropyl)-benzamide (m.p. 138°-140° C.) .

Provenance & Evidence