Ethanol → 3-[(2-Furanylmethyl)thio]propanoic acid, hydrazide
反応式
O1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6][CH2:7][CH2:8][C:9]([O:11]CC)=O.[OH2:14].[NH2:15][NH2:16].[CH3:17]CO>>[O:14]1[CH:17]=[CH:5][CH:4]=[C:3]1[CH2:2][S:6][CH2:7][CH2:8][C:9]([NH:15][NH2:16])=[O:11]参加物
4
実験手順
To a stirring 10 mL EtOH solution of 4.29 g (20 mmol) of ethyl 3-(furylthio)propanoate was added 0.71 g (22 mmol) of hydrazine hydrate. After heating at reflux for 24 hours, the reaction was stirred for 24 hours at room temperature. The solvent was then removed under vacuum, and the residue was dissolved in EtOH and filtered through a bed of charcoal. 2.77 g (69%) of product, which was a water white viscous liquid, was recovered and was employed immediately in the manner described in Example 13, below.
後処理
- temperatureAfter heating
- temperatureat reflux for 24 hours
- customThe solvent was then removed under vacuum
- dissolutionthe residue was dissolved in EtOH
- filtrationfiltered through a bed of charcoal
- customwas recovered
出典と根拠
- ORDレコード
- ord-3bcde93d7a07449eaca4a7cf2c4dded8
- 出典データセット
- uspto-grants-1995_01
- 特許番号
- US05378840
反応ノート
読み込み中…