反应详情

To a stirring 10 mL EtOH solution of 4.29 g (20 mmol) of ethyl 3-(furylthio)propanoate was added 0.71 g (22 mmol) of hydrazine hydrate. After heating at reflux for 24 hours, the reaction was stirred for 24 hours at room temperature. The solvent was then removed under vacuum, and the residue was dissolved in EtOH and filtered through a bed of charcoal. 2.77 g (69%) of product, which was a water white viscous liquid, was recovered and was employed immediately in the manner described in Example 13, below.

1. temperatureAfter heating
2. temperatureat reflux for 24 hours
3. customThe solvent was then removed under vacuum
4. dissolutionthe residue was dissolved in EtOH
5. filtrationfiltered through a bed of charcoal
6. customwas recovered