L-Tartaric acid → HCID 86748375, compound

HRID 1768957Notes

Reaction equation

HRID 1768957 reaction equation
[C:1]([OH:10])(=[O:9])[C@@H:2]([C@H:4]([C:6]([OH:8])=[O:7])[OH:5])[OH:3]>O>[OH2:3].[OH2:3].[OH2:3].[C:6]([CH:4]([CH:2]([C:1]([OH:10])=[O:9])[OH:3])[OH:5])([OH:8])=[O:7].[C:6]([CH:4]([CH:2]([C:1]([OH:10])=[O:9])[OH:3])[OH:5])([OH:8])=[O:7]

Participants

3

Reactant 1

HCID 444305L-Tartaric acid

Product 1

HCID 86748375HCID 86748375, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

3.91 g (9.5 mmol) of the above product was added to a solution of L(+)-tartaric acid (3.54 g, 23.6 mmol) in water (60 ml) and the solids were dissolved by heating to reflux. The hot solution was treated with decolorizing carbon, filtered and allowed to cool. The separated crystals were collected, washed with water and acetonitrile and dried to give the ditartrate-trihydrate of the title compound, mp. 185°-190° C., yield of the salt formation: 66.9%.

Workup

  1. dissolutionthe solids were dissolved
  2. temperatureby heating to reflux
  3. additionThe hot solution was treated with decolorizing carbon
  4. filtrationfiltered
  5. temperatureto cool
  6. customThe separated crystals were collected
  7. washwashed with water and acetonitrile
  8. customdried

Sources & evidence

ORD record
ord-a28b0021cbae400ea0c05ccf30484909
Source dataset
uspto-grants-1995_01
Patent number
US05380724

Reaction notes

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