L-Tartaric acid → HCID 86748375, compound

HRID 1768958Notes

Reaction equation

HRID 1768958 reaction equation
[C:1]([OH:10])(=[O:9])[C@@H:2]([C@H:4]([C:6]([OH:8])=[O:7])[OH:5])[OH:3]>O>[OH2:3].[OH2:3].[OH2:3].[C:6]([CH:4]([CH:2]([C:1]([OH:10])=[O:9])[OH:3])[OH:5])([OH:8])=[O:7].[C:6]([CH:4]([CH:2]([C:1]([OH:10])=[O:9])[OH:3])[OH:5])([OH:8])=[O:7]

Participants

3

Reactant 1

HCID 444305L-Tartaric acid

Product 1

HCID 86748375HCID 86748375, compoundYield 65.8%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of the protected compound obtained according to Example 38 (0.26 g, 0.5 mmol) and L(+)-tartaric acid (0.23 g, 1.5 mmol) in water (2.5 ml) was heated under reflux for one hour and allowed to cool to room temperature. The separated precipitate was collected to give the ditartrate-trihydrate of the title compound which was identical with the salt obtained according to Method A) above, yield: 65.8%, mp 169°-175° C.

Workup

  1. additionA mixture of the protected compound
  2. customobtained
  3. temperaturewas heated
  4. temperatureunder reflux for one hour
  5. customThe separated precipitate was collected

Sources & evidence

ORD record
ord-7164aee1d9a742fab7177d5c7043c5a3
Source dataset
uspto-grants-1995_01
Patent number
US05380724

Reaction notes

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