Hydrogen Bromide → HCID 18947065, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.5 g (1.54 mmol) of 1-carboxy-5-tosyl-5,6-dihydro-4H-thieno[3,4-c]pyrrole and 5 ml of a 33% solution of hydrobromic acid in acetic acid, placed in a sealed tube, is heated at 60° C. in a water bath for 15 min. The reaction mixture is then cooled, the precipitate formed is filtered, washed twice with diethyl ether and dried. 0.32 g of product is obtained in the hydrobromide form. Yield 83%. Melting point: 281.3°-281.7° C.

Provenance & Evidence