Hydrochloric Acid → HCID 18947060, compound

Participants

Reaction Steps

A stream of hydrochloric acid is passed into a suspension of 3.3 g (13.2 mmol) of 1-carboxy-5,6-dihydro-4H-thieno[3,4-c]pyrrole hydrobromide in 75 ml of ethanol, heated at reflux for 4 h. The solvent is then evaporated and the residue triturated with twice 20 ml of diethyl ether. 2.46 g of a beige solid are obtained. Yield 80%. Melting point: 163° C. (with decomposition).

Provenance & Evidence