HRID1769374

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12

HCID60923

Quiflapon

C34H35ClN2O3S

结构：COC(=O)C(C)(C)Cc1c(C(C)(C)C)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1

HCID18947566

未命名化合物

PRODUCTS

生成物

结构：CC(C)(Cc1c(C(C)(C)C)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1)C(=O)O

HCID18947537

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the conditions described in Step B of Example 1, but substituting the ester from Step B for the ester of Example 1. The title compound was recrystallized from EtOAc-EtOH; m.p. 201°-202° C. Anal. Calc. C 73.57; H 6.36; N 5.05 Found C 73.75; H 6.37; N 5.03.

WORKUP

后处理

customThe title compound was recrystallized from EtOAc-EtOH

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4ef98ad75b2d40ae910dd6dfb656912f
来源数据集: uspto-grants-1995_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05380850
来源说明: uspto-grants-1995_01

反应 SMILES

[Cl:1][C:2]1[CH:41]=[CH:40][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([O:16][CH2:17][C:18]4[CH:27]=[CH:26][C:25]5[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=5)[N:19]=4)=[CH:13][CH:14]=3)[C:9]([C:28]([CH3:31])([CH3:30])[CH3:29])=[C:8]2[CH2:32][C:33]([CH3:39])([CH3:38])[C:34]([O:36]C)=[O:35])=[CH:4][CH:3]=1.ClC1C=CC(CN2C3C(=CC(OCC4C=CC5C(=CC=CC=5)N=4)=CC=3)C(SC(C)(C)C)=C2CC(C)(C)C(O)=O)=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([O:16][CH2:17][C:18]4[CH:27]=[CH:26][C:25]5[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=5)[N:19]=4)=[CH:13][CH:14]=3)[C:9]([C:28]([CH3:31])([CH3:29])[CH3:30])=[C:8]2[CH2:32][C:33]([CH3:39])([CH3:38])[C:34]([OH:36])=[O:35])=[CH:40][CH:41]=1