Cyclopropanecarbonyl chloride → 3-[N-(4-Chlorobenzyl)-3-cyclopropanecarbonyl-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid

Participants

Reaction Steps

The title compound was prepared according to the conditions described in Step B and Step C of Example 47, from methyl 3-[N-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoate (prepared in Step A of Example 47), but using cyclopropanecarbonyl chloride in place of trimethylacetyl chloride in Step B. Anal. C, H, N for sodium salt·1 H2O: Calc. C 67.27; H 5.31; N 4.61 Found C 67.27; H 5.16; N. 4.58.

Provenance & Evidence