Hydrogen Bromide → HCID 20096775, compound

Participants

Reaction Steps

4-(3',4',5'-Trifluorophenyl)-1-(2'-hydroxyethyl)cyclohexane (10.4 g) was added to an aqueous solution of 47% HBr (15 ml), followed by stirring the mixture under reflux for 2 hours, adding the reaction solution to water (50 ml), extracting with ethyl acetate (100 ml), washing the organic layer with water, drying over anhydrous MgSO4, and concentrating the solvent under reduced pressure, to obtain 4-(3',4',5'-trifluorophenyl)-1 -(2'-bromoethyl)cyclohexane (10.4g).

Provenance & Evidence