2-Methoxyethylamine → HCID 20096999, compound

Participants

Reaction Steps

A solution of 1.8 g (24 mmol) of methoxyethylamine in 5 ml of methanol is added dropwise to a suspension of 4.0 g (24 mmol) of 7-methoxy[1,2,5]oxadiazolo[3,4-d]pyrimidine-1-oxide in 120 ml of methanol. The starting material goes into solution and immediately thereafter the product precipitates from the reaction mixture. After 30 minutes, the precipitate is filtered off with suction and washed with methanol. 3.4 g (68%) of 7-(2-methoxyethylamino)-[1,2,5]oxadiazolo[3,4-d]pyrimidine-1-oxide are obtained.

Provenance & Evidence