Ammonia → 1-Nitro-4-phenoxybenzene

Participants

Reaction Conditions

Reaction Steps

157.6 g of p-chloronitrobenzene and 116.1 g of sodium phenolate were initially introduced into a steel autoclave. At room temperature, 100 g of liquid ammonia were pumped into the pressure vessel, the mixture was heated to 70° C. and allowed to completely react with stirring over a period of 9 hours. The pressure of 28 bar initially observed dropped during the reaction to 22 bar. Removal of the ammonia by distillation and workup of the distillation residue gave-4-nitrodiphenyl ether with a yield of 213.8 g=99.4% of the theoretical yield. The product is 99.2% pure.

Provenance & Evidence