HuagongsheHuagongshe Chemistry Print Report · For research reference only
Monobasic potassium phosphate → Ribavirin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Monobasic potassium phosphate | HCID 516951 | — |
| Reactant | HCID 178418936 | HCID 178418936 | — |
| Reactant | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxypurin-9-yl)oxolane-3,4-diol | HCID 178521066 | — |
| Product | Ribavirin | HCID 37542 | — |
Reaction Steps
By using a substrate solution (pH 6.0) containing 40 mM triazole as the base donor, 60 mM inosine as the saccharide residue donor and 40 mM potassium dihydrogenphosphate, reactions were carried out in the same manner as in Example 1 at respective reaction temperature (40° to 70° C.) for 24 hours to produce ribavirin. The results are shown in Table 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05384251 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-6a291c8c92784860a8195839aa28a1c9 |
| Source note | uspto-grants-1995_01 |