Propyl chloroformate → HCID 10270365, compound

HRID 1769976Notes

Reaction equation

HRID 1769976 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH2:9][C:10]2[CH:15]=[C:14]([Cl:16])[CH:13]=[C:12]([Cl:17])[CH:11]=2)=[CH:4][C:3]=1[N+:18]([O-])=O.Cl[C:22]([O:24][CH2:25][CH2:26][CH3:27])=[O:23].C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl>>[NH2:18][C:3]1[CH:4]=[C:5]([NH:8][CH2:9][C:10]2[CH:15]=[C:14]([Cl:16])[CH:13]=[C:12]([Cl:17])[CH:11]=2)[CH:6]=[CH:7][C:2]=1[NH:1][C:22]([O:24][CH2:25][CH2:26][CH3:27])=[O:23]

Participants

4

Reactant 3

HCID 7998Propyl chloroformateHCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 20096585HCID 20096585, compound

Product 1

HCID 10270365HCID 10270365, compoundYield 58.7%

Procedure

A suspension of 15.5 g (50 mmol) 2-amino-5-(3,5-dichlorobenzylamino)-nitrobenzene is hydrogenated in a manner analogous with Example 1 (variant A) and worked up appropriately with 6.2 g (51 mmol) propyl chloroformate. 10.8 g of the end product are obtained in the form of the dihydrochloride. This forms colorless to pale pink crystals.

Sources & evidence

ORD record
ord-a89eaf49e4fe4b74be67ef84fd7a667e
Source dataset
uspto-grants-1995_01
Patent number
US05384330

Reaction notes

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