反应详情

Then, 0.89 g (3.2 mM) of 2-octylindan-5-boronic acid, 1.00 g (3.2 mM) of 5-bromo-2-octylindan, 2 ml of ethanol, 4 ml of benzene, 4 ml of 2M-sodium carbonate aqueous solution and 0.12 g of tetrakis(triphenylphosphine)palladium (O) were mixed and heat-refluxed for 1.5 hours under stirring. After the reaction, the reaction mixture was poured into ice water to precipitate a crystal. The crystal was recovered by filtration under reduced pressure and purified by silica gel column chromatography (eluent: toluene) and recrystallized from a mixture solvent (toluene/methanol) to obtain 1.22 g (2.66 mM) of 5,5'-bi-2-octyl)indan (Yield: 83%). ##STR320##

1. temperatureheat-refluxed for 1.5 hours
2. customAfter the reaction
3. customto precipitate a crystal
4. filtrationThe crystal was recovered by filtration under reduced pressure
5. custompurified by silica gel column chromatography (eluent: toluene)
6. customrecrystallized from a mixture solvent (toluene/methanol)