HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → 8-Azaspiro(4.5)decane-7,9-dione, 8-(4-((3,4-dihydro-2H-1-benzothiopyran-8-yl)oxy)butyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3,4-dihydro-2H-1-benzothiopyran-8-ol | HCID 121617 | — |
| Reactant | 8-(4-Bromobutyl)-8-azaspiro(4.5)decane-7,9-dione | HCID 11208851 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 8-Azaspiro(4.5)decane-7,9-dione, 8-(4-((3,4-dihydro-2H-1-benzothiopyran-8-yl)oxy)butyl)- | HCID 3073905 | — |
Reaction Steps
2 g (6.62 mmol) of 8-(4-bromobutyl)-8-azaspiro[4.5]decane-7,9-dione, 2.5 g (18.04 mmol) of potassium carbonate and a catalytic amount of potassium iodide are added, with stirring, to 1 g (6.015 mmol) of 8-thiochromanol dissolved in 10 cm3 of N,N-dimethylformamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05385930 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-bf64e2c4e38c42e781772b7fefc821ac |
| Source note | uspto-grants-1995_01 |