Gamma-Butyrolactone → HCID 15767531, compound

Participants

Reaction Conditions

Reaction Steps

360 grams of butoxypropylamine (2.75 moles) and 250 grams of butyrolactone (3.0 moles) were charged to a 1-liter stainless steel autoclave. After purging, the mixture was heated to 275° C. for six hours. The reactor was then cooled and the product discharged. The product was distilled with a simple Vigreux column, initially at atmospheric pressure to remove by-product water and then under vacuum (<1 mm) to recover the product. Butoxypropyl Pyrrolidone distills at about 135° C. to 145° C. under these conditions. The recovery was 391.2 grams of>98% pure Butoxypropyl Pyrrolidone.

Provenance & Evidence