反应详情

Propyleneurea of 30.0 g (0.3 mol), ethylchloroformate of 10.9 g (0.1 mol) and dichloroethane of 100 g were charged in a reaction vessel and refluxed at 85° to 88° C. A solution of triethylamine of 10.1 g (0.1 mol) in dichloroethane of 250 g was added drop by drop to the refluxed mixture in 2.5 hours followed by continuing for further 2 hours. The resulting solution was condensated and a crude product was refined by the column chromatography to obtain ethoxycarbonylpropyleneurea of 2.2 g (12.7%).

1. temperaturerefluxed at 85° to 88° C