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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1770674Generated: November 4, 2026

Pyroglutamate → (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine pyroglutamate salt

https://huagongshe.com/reaction/1770674

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyroglutamateHCID 5289118—
ReactantHCID 56929575HCID 56929575—
Product(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine pyroglutamate saltHCID 86702388—

Reaction Steps

The aqueous solubility of Compound 1 pyroglutamate was determined to be >161.5 mg/mL at pH 3.94.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09248133B2
Source datasetuspto-grants-2016_02
ORD IDord-dcba436418164a518817851e06e91f94
Source noteuspto-grants-2016_02