反应详情

30 g of 1H-benzo[d]imidazole-6-carboxylic acid ethyl ester (0.16 mol) and 150 mL anhydrous ethyl alcohol were added to a three-necked bottle, to which 50 mL of 80% hydrazine hydrate was added. After refluxing for 4 h, the ethyl alcohol was evaporated under reduced pressure and water was added to the residual solution to isolate a solid. After sucking filtration and drying, 24.9 g solid was obtained. Yield: 88%. MS: 177 (M+1).

1. additionwas added
2. temperatureAfter refluxing for 4 h
3. customthe ethyl alcohol was evaporated under reduced pressure and water
4. additionwas added to the residual solution
5. customto isolate a solid
6. filtrationfiltration
7. customdrying