HCID 178418750, compound → HCID 178515947, compound

HRID 1771258Notes

Reaction equation

HRID 1771258 reaction equation
[CH:1]1[CH:20]=[CH:19][C:17](=[O:18])/[C:3](=[CH:4]/[NH:5][CH2:6][CH2:7][NH:8]/[CH:9]=[C:10]2/[CH:11]=[CH:12][CH:13]=[CH:14][C:15]/2=[O:16])/[CH:2]=1.[Zn:21](CC)CC>C1COCC1>[CH:12]1[CH:13]=[CH:14][C:15](=[O:16])/[C:10](=[CH:9]/[NH:8][CH2:7][CH2:6][NH:5]/[CH:4]=[C:3]2/[CH:2]=[CH:1][CH:20]=[CH:19][C:17]/2=[O:18])/[CH:11]=1.[Zn:21]

Participants

4

Reactant 2

HCID 178418750HCID 178418750, compoundHCID 178515945HCID 178515945, compound

Product 1

HCID 178515947HCID 178515947, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
25 °C

Procedure

THF was added to a mixture of Salen and Et2Zn via a syringe under argon. The reaction mixture was stirred at 25° C. for 24 hours. The crude product was isolated from the concentrated reaction mixture by removal of the solvent under reduced pressure. A pure product Salen-Zn was obtained after recrystallization using THF and water.

Workup

  1. customThe crude product was isolated from the concentrated reaction mixture by removal of the solvent under reduced pressure

Sources & evidence

ORD record
ord-f719b77e5468414f884a3afc7ca273b5
Source dataset
uspto-grants-2016_02
Patent number
US09249120B2

Reaction notes

Loading…