HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(4-Fluoro-phenyl)-[1,2,4]triazin-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 67362865 | HCID 67362865 | — |
| Product | 5-(4-Fluoro-phenyl)-[1,2,4]triazin-3-ylamine | HCID 7176088 | 74% |
Reaction Steps
5-(4-Fluorophenyl)-1,2,4-triazin-3-amine (2.80 g, 74%) was prepared from 3-(methylsulfonyl)-5-(4-fluorophenyl)-1,2,4-triazine (5.00 g, 19.7 mmol) and 0.5 M ammonia in THF (100 mL, 50.0 mmol) according to the general procedure of Preparation 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249130B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-524d3b730c694b7d8138418910b95ba3 |
| Source note | uspto-grants-2016_02 |