Ammonia → HCID 67363740, compound

HRID 1771302Notes

Reaction equation

HRID 1771302 reaction equation
CS([C:5]1[N:6]=[N:7][CH:8]=[C:9]([C:11]2[N:16]=[CH:15][CH:14]=[CH:13][N:12]=2)[N:10]=1)(=O)=O.[NH3:17]>C1COCC1>[N:12]1[CH:13]=[CH:14][CH:15]=[N:16][C:11]=1[C:9]1[N:10]=[C:5]([NH2:17])[N:6]=[N:7][CH:8]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 67363009HCID 67363009, compound

Product 1

HCID 67363740HCID 67363740, compoundYield 23%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

5-(Pyrimidin-2-yl)-1,2,4-triazin-3-amine (1.0 g, 23%) was prepared from 3-(methylsulfonyl)-5-(pyrimidin-2-yl)-1,2,4-triazine (5.0 g, crude) and 0.5 M ammonia in THF (20 mL) according to the general procedure of Preparation 2.

Workup

  1. customaccording to the general procedure of Preparation 2

Sources & evidence

ORD record
ord-e825d4793a5a44fea66d9a8afba932a7
Source dataset
uspto-grants-2016_02
Patent number
US09249130B2

Reaction notes

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