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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1771313Generated: October 30, 2026

4-Fluorophenylboronic acid → 6-(4-Fluorophenyl)-5-phenyl-1,2,4-triazin-3-amine

https://huagongshe.com/reaction/1771313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylboronic acidHCID 285645—
Reactant6-Bromo-5-phenyl-1,2,4-triazin-3-amineHCID 86676114—
Product6-(4-Fluorophenyl)-5-phenyl-1,2,4-triazin-3-amineHCID 6736367646.5%

Reaction Steps

6-(4-Fluorophenyl)-5-phenyl-1,2,4-triazin-3-amine (99 mg, 46%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.21 g, 0.80 mmol) and 4-fluorophenylboronic acid (0.112 g, 0.80 mmol) according to the general procedure of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249130B2
Source datasetuspto-grants-2016_02
ORD IDord-4ed496f5542542f1b6b66d61edc587ee
Source noteuspto-grants-2016_02