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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1771379Generated: November 2, 2026

Trifluoroacetic acid → HCID 53354109, compound

https://huagongshe.com/reaction/1771379

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86676122HCID 86676122—
SolventDichloromethaneHCID 6344—
ProductHCID 53354109HCID 5335410971.4%

Reaction Steps

6-(6-(Methylamino)pyridin-3-yl)-5-phenyl-1,2,4-triazin-3-amine (49.5 mg, 0.177 mmol, 71.4%) was prepared from 5-(3-amino-5-phenyl-1,2,4-triazin-6-yl)pyridin-2-yl(methyl)carbamate (vide supra), by BOC deprotection with trifluoroacetic acid (0.4 mL) in dichloromethane (1.6 mL) for 1 hour at room temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249130B2
Source datasetuspto-grants-2016_02
ORD IDord-a540679e163240c7840088eaeea78564
Source noteuspto-grants-2016_02