HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 53354109, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86676122 | HCID 86676122 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53354109 | HCID 53354109 | 71.4% |
Reaction Steps
6-(6-(Methylamino)pyridin-3-yl)-5-phenyl-1,2,4-triazin-3-amine (49.5 mg, 0.177 mmol, 71.4%) was prepared from 5-(3-amino-5-phenyl-1,2,4-triazin-6-yl)pyridin-2-yl(methyl)carbamate (vide supra), by BOC deprotection with trifluoroacetic acid (0.4 mL) in dichloromethane (1.6 mL) for 1 hour at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249130B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-a540679e163240c7840088eaeea78564 |
| Source note | uspto-grants-2016_02 |