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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1771387Generated: November 2, 2026

Azetidine → HCID 53354625, compound

https://huagongshe.com/reaction/1771387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzetidineHCID 10422—
ReactantHCID 86676123HCID 86676123—
ProductHCID 53354625HCID 5335462519%

Reaction Steps

6-[2-(Azetidin-1-yl)-6-(trifluoromethyl)pyridin-4-yl]-5-phenyl-1,2,4-triazin-3-amine (20.0 mg, 19%) was prepared from 5-phenyl-6-(2-chloro-6-trifluoromethyl-pyridin-4-yl)-1,2,4-triazin-3-amine (100 mg, 0.28 mmol) and azetidine according to the general procedure for Preparation 4a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249130B2
Source datasetuspto-grants-2016_02
ORD IDord-2c57b8d3537b4a0a89aeb77361d59f58
Source noteuspto-grants-2016_02