HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 118235991, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| Reactant | HCID 178441178 | HCID 178441178 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 118235991 | HCID 118235991 | — |
Reaction Steps
To a solution of 5-(5-amino-3-(tert-butyl)-1H-pyrazol-1-yl)pyridin-2-ol (Abraham, S. et al., WO 2009/117080, 24 Sep. 2009) (4.04 g, 17.4 mmol) in MeCN (50 mL) was added 4-(2-chloroethyl)morpholine hydrochloride (3.88 g, 20.9 mmol) and K2CO3 (5.29 g, 38.3 mmol)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249125B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-599946fc7b21479b82c772ee9e619c25 |
| Source note | uspto-grants-2016_02 |