HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → HCID 89852940, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | HCID 55250755 | HCID 55250755 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 89852940 | HCID 89852940 | — |
Reaction Steps
The mixture of 5-methylisochroman-1-carboxylic acid (1 g), methanol (20 ml) and trimethylsilylchloride (2 ml) was stirred for 1.5 hrs and volatiles evaporated. Separation method E yielded the title compound (0.5 g) as yellowish oil. Alternatively sulphuric acid can be used instead of trimethylsilylchloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249127B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-08bfca2cdd824fabb897ded7ea71b51c |
| Source note | uspto-grants-2016_02 |