HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetamide → HCID 71765898, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetamide | HCID 178 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 71766907 | HCID 71766907 | — |
| Catalyst | Zinc Chloride | HCID 5727 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 71765898 | HCID 71765898 | — |
Reaction Steps
The mixture of 1-(4,5-dihydro-1H-imidazol-2-yl)isochroman-5-carbonitrile (example 5, 75 mg), acetamide (39 mg), zink chloride (45 mg), THF (0.5 ml) and water (0.5 ml) was heated in a microwave reactor for 50 seconds at 320 W. The title compound was purified by applying method A. (Yield 15 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249127B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-6038a7abf8234ff4bbe99a25a0c0e96e |
| Source note | uspto-grants-2016_02 |