HCID 89851713, compound → HCID 89851565, compound

Participants

Reaction Steps

To a solution of 1-(2-(benzyloxy)-4,4-difluorobutyl)-2-methylbenzene (10 g, 34.48 mmol) in MeOH (150 ml) was added 10% Pd/C (1.0 g) under nitrogen and stirred at 40 psi for 5 h. The reaction mixture was filtered through Celite and concentrated under reduced pressure to afford crude compound. The title compound was purified by separation method E. (Yield 6.0 g).

Provenance & Evidence