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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1771532Generated: November 3, 2026

2-Fluoroethylamine → 1-(2-Fluoroethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea

https://huagongshe.com/reaction/1771532

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluoroethylamineHCID 9996—
ReactantPhenyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamateHCID 58885831—
Product1-(2-Fluoroethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ureaHCID 44607353—

Reaction Steps

Method as described for intermediate 13 using phenyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (intermediate 17) and 2-fluoroethylamine to afford a pink wax (3.8 g) used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249129B2
Source datasetuspto-grants-2016_02
ORD IDord-69e6082ea8d7460989050d2c2d64e145
Source noteuspto-grants-2016_02