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HRID1771536

反应详情

EQUATION

反应方程式

HRID 1771536 的结构方程式

REACTANTS

反应物

3
结构：Clc1ccnc(Cl)n1
HCID77531

2,4-Dichloropyrimidine

C4H2Cl2N2

结构：CC1(C)OB(c2ccc([N+](=O)[O-])cc2)OC1(C)C
HCID2773555

4,4,5,5-tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane

C12H16BNO4

结构：CSc1nc(-c2cncc(F)c2)cc(N2CCOC[C@@H]2C)n1
HCID67382782

未命名化合物

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1ccc(-c2ccnc(Cl)n2)cc1
HCID11053626

未命名化合物

收率 53%

PROCEDURE

实验过程

Method as described for intermediate 5 using 4,4,5,5-tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane and 2,4-dichloropyrimidine. The mixture was purified using flash chromatography (0-100% EtOAc in petroleum ether 40-60) to afford the title compound (1.45 g, 53%)

WORKUP

后处理

  1. customThe mixture was purified