反应详情

Method as described for Example 8 using 1-(4-(6-chloro-2-morpholinopyrimidin-4-yl)phenyl)-3-ethylurea and (2-methylsulfonylphenyl)boronic acid. The reaction mixture was concentrated in vacuo, and the residue dissolved in DMSO, filtered and purified by prep HPLC (low pH) to afford a white solid (13.2 mg, 10%).

1. concentrationThe reaction mixture was concentrated in vacuo
2. dissolutionthe residue dissolved in DMSO
3. filtrationfiltered
4. custompurified by prep HPLC (low pH)