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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1771550Generated: October 25, 2026

Morpholine → 1-(4-(4-Morpholinopyrimidin-2-yl)phenyl)-3-propylurea

https://huagongshe.com/reaction/1771550

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant4-(2-Chloropyrimidin-4-yl)morpholineHCID 1714697—
Reactant1-Propyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ureaHCID 44119578—
Product1-(4-(4-Morpholinopyrimidin-2-yl)phenyl)-3-propylureaHCID 53380745—

Reaction Steps

Method as described for Example 34 using (4-(3-propylureido)phenyl)boronic acid pinacol ester and 4-(2-chloropyrimidin-4-yl)morpholine which was synthesised according to Intermediate 3, using morpholine as starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249129B2
Source datasetuspto-grants-2016_02
ORD IDord-726fcf0bbe73493c9e5d29463d1eb0bc
Source noteuspto-grants-2016_02