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HRID1771552

反应详情

EQUATION

反应方程式

HRID 1771552 的结构方程式

REACTANTS

反应物

3
结构：CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1
HCID44119377

N-Ethyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea

C15H23BN2O3

结构：CSc1nc(-c2cncc(F)c2)cc(N2CCOC[C@@H]2C)n1
HCID67382782

未命名化合物

结构：C[C@H]1COCCN1c1nccc(Cl)n1
HCID87379247

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CCNC(=O)Nc1ccc(-c2ccnc(N3CCOC[C@@H]3C)n2)cc1
HCID53380859

未命名化合物

PROCEDURE

实验过程

Method as described for intermediate 5 using (S)-4-(4-chloropyrimidin-2-yl)-3-methylmorpholine (intermediate 15) and 4-(3-ethylureido)phenyl boronic acid pinacol ester. Material was purified by prep HPLC (low pH) to afford a brown solid, (77 mg, 40%).

WORKUP

后处理

  1. customMaterial was purified by prep HPLC (low pH)
  2. customto afford a brown solid, (77 mg, 40%)