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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1772154Generated: October 30, 2026

N-bromobutanimide → Methyl 4-(Bromomethyl)-2-tert-butylthiazole-5-carboxylate

https://huagongshe.com/reaction/1772154

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
ReactantMethyl 4-methyl-2-tert-butylthiazole-5-carboxylateHCID 59734470—
Reactant3-((3-Bromo-2-methylphenylamino)methyl)-5-tert-butylthiophene-2-carboxylic AcidHCID 86697932—
SolventCarbon TetrachlorideHCID 5943—
ProductMethyl 4-(Bromomethyl)-2-tert-butylthiazole-5-carboxylateHCID 66610676—

Reaction Steps

Using the same general procedure as described for the preparation of 102e, reaction of methyl 4-methyl-2-tert-butylthiazole-5-carboxylate with N-bromo-succinimide in carbon tetrachloride afforded 125a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09249123B2
Source datasetuspto-grants-2016_02
ORD IDord-bd38f8fb59d04dec882a49780967104f
Source noteuspto-grants-2016_02