HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminooxetane-3-carboxylic acid → 4'-(4-Chlorophenyl)-2',3',9'-trimethylspiro[oxetane-3,6'-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminooxetane-3-carboxylic acid | HCID 15024256 | — |
| Reactant | 3-Amino-1-[(tert-butoxy)carbonyl]azetidine-3-carboxylic acid | HCID 53414710 | — |
| Reactant | 4'-(4-Chlorophenyl)-2',3',9'-trimethylspiro[azetidine-3,6'-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine] | HCID 57405432 | — |
| Product | 4'-(4-Chlorophenyl)-2',3',9'-trimethylspiro[oxetane-3,6'-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine] | HCID 57405433 | — |
Reaction Steps
A procedure analogous to the scheme set forth for the synthesis of Compound 224 was followed, with the exception that 3-aminooxetane-3-carboxylic acid was used as starting material instead of 3-amino-1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249161B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-64fa008fe1d4450abbbe7556a3ea583d |
| Source note | uspto-grants-2016_02 |