3,7-Dimethyloctyl trichlorosilane → Bis(3,7-dimethyloctyl)dichlorosilane
Reaction equation
[CH3:1][CH:2]([CH2:9][CH2:10][CH2:11][CH:12]([CH3:14])[CH3:13])[CH2:3][CH2:4][Si:5]([Cl:8])([Cl:7])Cl.[CH3:15][CH:16]([CH2:21][CH2:22][CH2:23][CH:24]([CH3:26])[CH3:25])[CH2:17][CH2:18][Mg]Br>O1CCCC1>[CH3:15][CH:16]([CH2:21][CH2:22][CH2:23][CH:24]([CH3:26])[CH3:25])[CH2:17][CH2:18][Si:5]([CH2:4][CH2:3][CH:2]([CH3:1])[CH2:9][CH2:10][CH2:11][CH:12]([CH3:13])[CH3:14])([Cl:7])[Cl:8]Participants
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- -20 °C
Procedure
Tetrahydrofuran (50 mL) and 3,7-dimethyloctyl trichlorosilane (11.27 g, 40.9 mmol) were placed in a 200 mL four-necked flask in a nitrogen atmosphere, and cooled to −20° C. 3,7-dimethyloctyl magnesium bromide (Sigma-Aldrich Co. LLC., 1.0 M, 42.9 ml) as added dropwise, and the mixture was agitated for 1 hour at 10° C. or less. The temperature was raised gradually to room temperature over the course of about 1 hour, and the mixture was left standing overnight. The precipitated salt was filtered out, the tetrahydrofuran was removed by concentration under reduced pressure, and distillation under reduced pressure was performed to obtain the target bis(3,7-dimethyloctyl)dichlorosilane (Compound G21) (150-152° C./0.6 Torr, 11.3 g, yield 73%).
Workup
- temperatureThe temperature was raised gradually to room temperature over the course of about 1 hour
- waitthe mixture was left
- waitstanding overnight
- filtrationThe precipitated salt was filtered out
- customthe tetrahydrofuran was removed by concentration under reduced pressure, and distillation under reduced pressure
Sources & evidence
- ORD record
- ord-bb6998711cb24c8fa9636580d657194e
- Source dataset
- uspto-grants-2016_02
- Patent number
- US09249257B2
Reaction notes
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