HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 117732281, compound → Benzyl 4-(5-(2-(1-(tert-butoxycarbonyl)azetidin-3-yl)-8-morpholinoimidazo[1,2-a]pyrazin-5-yl)pyridin-2-yl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 117732281 | HCID 117732281 | — |
| Reactant | Benzyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate | HCID 131734676 | — |
| Product | Benzyl 4-(5-(2-(1-(tert-butoxycarbonyl)azetidin-3-yl)-8-morpholinoimidazo[1,2-a]pyrazin-5-yl)pyridin-2-yl)piperazine-1-carboxylate | HCID 117727918 | — |
Reaction Steps
Compound 29b was subjected to Suzuki coupling reaction conditions with benzyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate using the methods described in Example 1, Step G to obtain compound 29c. Mass Spectrum (LCMS, ESI pos.) Calcd. for C35H42N8O5: 655.3 (M+H). Found 655.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249163B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-dad0d4b1db2149c4935dc5daba09a8d1 |
| Source note | uspto-grants-2016_02 |