Hydrochloric Acid → HCID 22103383, compound

Participants

Reaction Steps

To a stirred suspension of (4-bromophenyl)hydrazine HCl (2.01 g, 8.81 mmol) in water (20 mL) was added conc. HCl (1 mL) followed by glyoxylic acid monohydrate (811 mg, 8.81 mmol). The mixture was stirred vigorously at rt for 30 min and the light yellow suspension was filtered, washed with water (3×15 mL), and dried under suction followed by high vacuum to afford compound 84a as a light yellow solid, used without further purification in the following step. Mass spectrum (LCMS, ESI pos.): Calcd. for C8H7BrN2O2, 243.0/245.0 (M+H). found 243.2/245.1.

Provenance & Evidence