HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 2-Chloro-N-(5,6-dimethoxypyridin-2-yl)pyridine-3-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Chloropyridine-3-sulfonyl chloride | HCID 10219968 | — |
| Reactant | 5,6-Dimethoxypyridin-2-amine | HCID 46739148 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Chloro-N-(5,6-dimethoxypyridin-2-yl)pyridine-3-sulfonamide | HCID 90022796 | 66.4% |
Reaction Steps
The title compound (549 mg, 1.66 mmol) was prepared from 2-chloropyridine-3-sulfonyl chloride (530 mg, 2.5 mmol), 5,6-dimethoxypyridin-2-amine (424 mg, 2.8 mmol) and pyridine (0.6 mL, 7.5 mmol) in DCM (10 mL) using the methods of (IntC1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-b14f3c065fb44b75b86ff0a99ce25084 |
| Source note | uspto-grants-2016_02 |