3,5-Dimethylaniline → HCID 43388285, compound

HRID 1772906Notes

Reaction equation

HRID 1772906 reaction equation
[Cl:1][C:2]1[C:7]([S:8](Cl)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([CH3:20])[CH:19]=1)[NH2:16]>O1CCOCC1>[Cl:1][C:2]1[C:7]([S:8]([NH:16][C:15]2[CH:17]=[C:18]([CH3:20])[CH:19]=[C:13]([CH3:12])[CH:14]=2)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 79493,5-DimethylanilineHCID 102199682-Chloropyridine-3-sulfonyl chloride

Product 1

HCID 43388285HCID 43388285, compoundYield 52.1%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound (791 mg, 2.67 mmol) was prepared from 2-chloropyridine-3-sulfonyl chloride (1.09 g, 5.12 mmol) and 3,5-dimethylaniline (709 uL, 5.65 mmol) in 1,4-dioxane (30 mL) using the methods of (IntC1).

Sources & evidence

ORD record
ord-8fdd2ac802e74c1fad18a8b8de6fc8b9
Source dataset
uspto-grants-2016_02
Patent number
US09249160B2

Reaction notes

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