HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-[(3,5-Dimethyl pyridin-2-yl)methyl]-2-(3,4-di methoxyphenyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(Chloromethyl)-3,5-dimethylpyridine | HCID 15594399 | — |
| Reactant | 2-(4-methoxy-3,5-dimethylphenyl)-4-(2,4,6-trifluorobenzyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide | HCID 72722085 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-[(3,5-Dimethyl pyridin-2-yl)methyl]-2-(3,4-di methoxyphenyl)-2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide | HCID 72720984 | — |
Reaction Steps
The title compound (89 mg, 0.20 mmol) was prepared from (IntA1) (167 mg, 0.50 mmol), K2CO3 (207 mg, 1.5 mmol) and 2-(chloromethyl)-3,5-dimethylpyridine (93 mg, 0.6 mmol) in DMF (5 mL) using the methods of (115).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-556f4ff14cc44d49a111b76f4da4c27e |
| Source note | uspto-grants-2016_02 |