HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 90054927, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 4-Chloro-2-fluorobenzylamine | HCID 2724910 | — |
| Reactant | HCID 64280908 | HCID 64280908 | — |
| Reactant | HCID 90054926 | HCID 90054926 | — |
| Product | HCID 90054927 | HCID 90054927 | — |
Reaction Steps
The title compound (110 mg, 0.23 mmol) was prepared in two steps from 4-Chloro-N-(3,4-dimethoxyphenyl)pyridine-3-sulfonamide (IntD1) (300 mg, 0.90 mmol), 2-fluoro-4-chlorobenzylamine (146 mg, 0.90 mmol) and K2CO3 (378 mg, 2.73 mmol); followed by 1,1′-carbonyldiimidazole (0.22 g, 1.32 mmol) using the methods of (91).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09249160B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-c5f15a6ffa724353b1ce00458ca34eac |
| Source note | uspto-grants-2016_02 |