Potassium Carbonate → HCID 90054923, compound

HRID 1772988Notes

Reaction equation

HRID 1772988 reaction equation
Br[CH2:2]C1CCCCC1.C([O-])([O-])=O.[K+].[K+].[Cl:15][C:16]1[CH:42]=[CH:41][CH:40]=[C:39]([F:43])[C:17]=1[CH2:18][N:19]1[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[S:22](=[O:30])(=[O:29])[N:21]([CH2:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34]N=2)[C:20]1=[O:38]>>[Cl:15][C:16]1[CH:42]=[CH:41][CH:40]=[C:39]([F:43])[C:17]=1[CH2:18][N:19]1[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[S:22](=[O:29])(=[O:30])[N:21]([CH2:31][CH:32]2[CH2:37][CH2:36][CH2:35][CH2:34][CH2:2]2)[C:20]1=[O:38]

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 137636Cyclohexane, (bromomethyl)-HCID 90054655HCID 90054655, compound

Product 1

HCID 90054923HCID 90054923, compound

Procedure

The title compound (25 mg, 0.06 mmol) was prepared from (IntE1) (0.3 g, 0.88 mmol), 2-(bromomethyl)cyclohexane (0.18 g, 1.05 mmol) and K2CO3 (0.36 g, 2.60 mmol) using the methods of (128).

Sources & evidence

ORD record
ord-594ac1f735874b9caf7d11ab80211d70
Source dataset
uspto-grants-2016_02
Patent number
US09249160B2

Reaction notes

Loading…