Hydrochloric Acid → 6-(4-Amino-2-fluorophenoxy)-N-(4-(benzyloxy)phenyl)pyrimidin-4-amine

HRID 177348Notes

Reaction equation

HRID 177348 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[cH:17][c:18]([O:22][c:23]3[c:24]([F:33])[cH:25][c:26]([NH:29][C:30](=[O:31])[CH3:32])[cH:27][cH:28]3)[n:19][cH:20][n:21]2)[cH:13][cH:14]1.[CH3:35][OH:36].[ClH:34]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[cH:17][c:18]([O:22][c:23]3[c:24]([F:33])[cH:25][c:26]([NH2:29])[cH:27][cH:28]3)[n:19][cH:20][n:21]2)[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59852842N-(4-(6-(4-(benzyloxy)phenylamino)pyrimidin-4-yloxy)-3-fluorophenyl)acetamide

Product 1

HCID 598530036-(4-Amino-2-fluorophenoxy)-N-(4-(benzyloxy)phenyl)pyrimidin-4-amine

Sources & evidence

ORD record
ord-1ae57370315f475fa0da5ffa69f86616
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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